Peptide Database

Peptide Name[DesNH2-Tyr1,D-Ala2,Ala15]GRF(1-29)-NH2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC150H247N43O43S

DescriptionStandard

        YADAIFTNSYRKVLAQLSARKLLQDIMSR
    

Molecular Weight3372.89 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0951

GRAVY Index-0.14

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index37.70

Aliphatic Index 104.48

Aromaticity 0.1034

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1441.11

LogP -13.36

H-bond Donors 52.0

H-bond Acceptors 47.0

Rotatable Bonds 115.0

Heavy Atoms 237.0

Ring Count 3.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269187 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyGHRH/CRF

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermChlorpheniramine M

C-TermAmidation

Other ModsD-residue notation at positions 2; Mixed L/D stereochemistry with D-annotated positions 2

Bio-Activity Profile

Function

Endocrine

MethodHPLC

Half-LifePorcine plasma, in vitro; 3600 s