Peptide Database

Peptide NameUnnamed

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC44H55N9O11S

DescriptionStandard

        YPFGFCQG
    

Molecular Weight918.03 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0314

GRAVY Index0.11

Hydrophobic Moment 0.15

Boman Index0.40

Instability Index38.83

Aliphatic Index 0.00

Aromaticity 0.3750

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 321.55

LogP -1.81

H-bond Donors 11.0

H-bond Acceptors 12.0

Rotatable Bonds 24.0

Heavy Atoms 65.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091246 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

RECORD: Rec_0208899 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

Targetmu opioid receptor

Activity0.08 μM

MethodIC50

PaperDooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.. Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995). PMID7670227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7670227/