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MYP_015492
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Basic Information
[Tyr]12-VmCT1-NH2 (Derived from VmCT1)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C76H106N16O17
Standard
Sequence
FLGALWNVAKSYF
Physicochemical Analysis
1515.75 Da
8.59
0.76
0.55
0.0583
0.78
0.44
0.45
30.41
97.69
0.3077
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
537.88
-1.21
19.0
18.0
45.0
109.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0061673 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0076537 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida tropicalis IOC 4560
6.3 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0099609 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae -12
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0139327 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0163673 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Micrococcus luteus A270
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
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