Peptide Database

Peptide NamePapMA-k (Derived from Papiliocin and Magainin 2)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC116H185N31O20

DescriptionStandard

        RWKIFKKIKKFLHSAKKF
    

Molecular Weight2333.91 Da

Isoelectric Point (pI)11.47

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.58

Charge Density (pH 7.0) 0.4356

GRAVY Index-0.76

Hydrophobic Moment 0.84

Boman Index-0.27

Instability Index18.77

Aliphatic Index 70.56

Aromaticity 0.2222

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 866.76

LogP -1.63

H-bond Donors 32.0

H-bond Acceptors 29.0

Rotatable Bonds 84.0

Heavy Atoms 167.0

Ring Count 6.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368952 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Other ModsThe 'k' in sequence is lysine peptoid

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

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