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MYP_015490
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Basic Information
PapMA-k (Derived from Papiliocin and Magainin 2)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C116H185N31O20
Standard
Sequence
RWKIFKKIKKFLHSAKKF
Physicochemical Analysis
2333.91 Da
11.47
7.84
7.58
0.4356
-0.76
0.84
-0.27
18.77
70.56
0.2222
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
866.76
-1.63
32.0
29.0
84.0
167.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017224 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
mouse macrophage-derived RAW264
42 μM
IC50
PMID26053120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26053120/
RECORD: Rec_0023706 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
4 μM
MIC
PMID26053120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26053120/
RECORD: Rec_0024192 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID26053120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26053120/
RECORD: Rec_0048248 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
2 μM
MIC
PMID26053120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26053120/
RECORD: Rec_0173742 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'k' in sequence is lysine peptoid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID26053120 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26053120/
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