Peptide Database

Peptide NameywoF signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC153H240N34O35S

DescriptionStandard

        MRKWYFILLAGVLTSVILAFVYDKTKA
    

Molecular Weight3147.81 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.27

Charge Density (pH 7.0) 0.0925

GRAVY Index0.89

Hydrophobic Moment 0.32

Boman Index0.32

Instability Index23.94

Aliphatic Index 130.00

Aromaticity 0.1852

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1114.12

LogP -2.32

H-bond Donors 41.0

H-bond Acceptors 39.0

Rotatable Bonds 102.0

Heavy Atoms 223.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344465 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

Activity0.0 U/mL

MethodCutinase activity assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/