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MYP_015419
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Basic Information
Brevinin-20a
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C149H249N43O40S2
Standard
Sequence
GLFNVFKGALKTAGKHVAGSLLNQLKCKVSGGC
Physicochemical Analysis
3346.96 Da
9.90
4.82
4.53
0.1461
0.29
0.57
0.17
-8.84
94.55
0.0606
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1343.26
-14.70
48.0
48.0
116.0
234.0
3.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013807 VERIFIED: NO
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
RECORD: Rec_0029324 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
10 μM
MIC
PMID11892844 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11892844/
RECORD: Rec_0113414 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 60.6%, E 0.0%, T 24.2%, C 15.2% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0149840 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
2.0 μM
MIC
PaperJ.B. Kim et al. / The Journal of Peptide Research 58 (2008) 349-356. Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris
RECORD: Rec_0191893 VERIFIED: YES
Provenance & Taxonomy
Rana ornativentris [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal
PaperJ.B. Kim et al. / The Journal of Peptide Research 58 (2008) 349-356. Antimicrobial peptides from the skin of the Japanese mountain brown frog, Rana ornativentris
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