Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC917H1391N205O284S9

DescriptionStandard

        IDDLAEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYTASPYVVAPFTVTDQSDSMLFLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMANEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20119.64 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.23

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0832

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index46.01

Aliphatic Index 92.19

Aromaticity 0.1311

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7740.30

LogP -84.36

H-bond Donors 263.0

H-bond Acceptors 278.0

Rotatable Bonds 641.0

Heavy Atoms 1415.0

Ring Count 34.0

Amide Bonds 197.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0086073 VERIFIED: NO

Provenance & Taxonomy

OrganismOnychorhynchus coronatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria