Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length478 amino acids

Chemical FormulaC2342H3735N627O671S14

DescriptionStandard

        MIWAFVFALLGACSRAAGTNAGLKGRVTQKGLEYGQQFGLEVVKSLLKKEHVPDLNGSYNIPLIGDVGYSVSRIQIQELQLNESVVSFSEGTGVRLVVSNARIHLSGVWRVKVLFVPDSGTFDLSVSDLSLSTELGVSRDDGGRPQVWSANCRSSVGRLDVKFHNGASWLYNLFMGALQVPLRYEVNRQLCPELGKGISNLERVLKTMQVSAQIDPFAAIDYSLVNKPVIAREHGDIDLKGEFYGVAKHTESPFSPVPFLLPDEGDHMLLLGLSEFSANSAAFVYFTAGALRKNFRDDTIPKRSPIRLNTGSMGLFLPELKKLYPDMPMELHLSARKQPLLTCLPDSLALALFGAAEAFVVLPNATLASAFLLDLDASVAGQLQLDSAKVGGSVALTNFSMSVVRSHVGSVQVKTLETLLKLALQMVALPMVNKKLKEGFPLPSVYNLSLVNPRVKINQGFVLVATDVQYQARAAVAG
    

Molecular Weight51860.42 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)4.20

Net Charge (pH 7.4) 3.42

Charge Density (pH 7.0) 0.0088

GRAVY Index0.16

Hydrophobic Moment 0.79

Boman Index0.13

Instability Index29.77

Aliphatic Index 105.00

Aromaticity 0.0795

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0403122 VERIFIED: NO

Provenance & Taxonomy

OrganismChelydra serpentina (Snapping turtle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria