Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length518 amino acids

Chemical FormulaC2441H3833N733O760S19

DescriptionStandard

        MGHRSDCYGRGTALEGDKTTTGAVCIASMSNDTEHGRRVMRVGDKTTRCPKCGEPGVVVSGEPRDTNMGKIAAVDGSVVRCACPSGSNWIIAPAGQWVGPGVDPSIAAQAQLFAERKAAQEAEEKRRAEEREHNRVFAKSCLRGEGCNDAGTQQEPHTNFADMGLFKAAPATDAATDSDAPQHAQTAKKKPPAPDIPKPKKRSTLYKWFNGNHEEMEYQAAVAAAASATRAQTATAGVNVLEQIGGRFATYGTWAVRGAEIATAGAGASVAGFLVGMMPGRLNDGEQDFIDRMRLAQMSEAPTRVRYTWENDSNGNPVPHGWHTPSGKDRVRVRKMQWDSTRQAYTFTTEEESPVTIIWTPDHSGVRTPSNTGNQTPLRLPGTILVNPLPDGTQITSTSTPAPDEKNFADYILILPVSDIPPIYIYLNADHKYHTAPKGAPPLPAFPDAKRAPRKTAIQGGGQLRARWKDSKGKIYEWDSQHGTVEVYDRSGRKHLGEFNHITGEQTKPADPTRKVEK
    

Molecular Weight56217.24 Da

Isoelectric Point (pI)8.63

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.0110

GRAVY Index-0.69

Hydrophobic Moment 0.86

Boman Index-0.09

Instability Index36.03

Aliphatic Index 57.93

Aromaticity 0.0656

Extinction Coeff. Reduced 72880.00

Extinction Coeff. Oxidized 73380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078957 VERIFIED: NO

Provenance & Taxonomy

OrganismLeclercia adecarboxylata [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence