Peptide Database

Peptide NameLH alpha 1-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC433H685N121O129S14

DescriptionStandard

        TMQGCPECKLKENKYFSKPDAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNVRVENHTECHCSTCYYHKS
    

Molecular Weight10098.71 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)6.56

Net Charge (pH 7.4) 6.04

Charge Density (pH 7.0) 0.0729

GRAVY Index-0.46

Hydrophobic Moment 0.62

Boman Index-0.08

Instability Index55.09

Aliphatic Index 41.22

Aromaticity 0.0889

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 8075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4019.36

LogP -45.95

H-bond Donors 149.0

H-bond Acceptors 153.0

Rotatable Bonds 328.0

Heavy Atoms 697.0

Ring Count 17.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0076165 VERIFIED: YES

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyLH alpha

Tax ID9940

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide5-29; 8-58; 26-80; 30-82; 57-85

Other Mods50:N-linked (GlcNAc...) asparagine; 76:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour