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MYP_015385
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Basic Information
Hemoglobin beta chain [031-037]
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
7 amino acids
C45H64N8O10
Standard
Sequence
LVVYPWT
Physicochemical Analysis
877.04 Da
5.52
-0.24
-0.45
-0.0344
1.10
0.17
0.62
-10.16
138.57
0.2857
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
285.38
1.22
10.0
10.0
21.0
63.0
4.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0264385 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Rattus norvegicus [Animal]
9913; 10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Toxin
L929
RECORD: Rec_0283079 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Spinorphin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory Myotropic
Mammalian: 5.5 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Spinorphin (Bos taurus): PMID 11829145 PMID11829145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11829145/
RECORD: Rec_0312539 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Opioid
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
PMID11829145 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11829145/
RECORD: Rec_0331599 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hemorphin
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-III Inhibitory
Dipeptidyl peptidase III
PaperChiba, T.; Li, Y.; Yamane, T.; Ogikubo, O.; Fukuoka, M.; Arai, R.; Takahashi, S.; Ohtsuka, T.; Ohkubo, I.; Matsui, N.. Inhibition of recombinant dipeptidyl peptidase III by synthetic hemorphin-like peptides. Peptides, 24, 773-778, 2003.
RECORD: Rec_0345500 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
PaperJung K. Y., Moon H. D., Lee G. E., Lim H. H., Park C. S., Kim Y. C.. Structure-activity relationship studies of spinorphin as a potent and selective human P2X(3) receptor antagonist. J. Med. Chem., 50, 4543-4547, 2007.
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