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MYP_015384
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Basic Information
Calcitonin
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
32 amino acids
C151H233N39O49S3
Standard
Sequence
CGNLSTCMLGTYTQDLNKFHTFPQTSIGVEAP
Physicochemical Analysis
3474.89 Da
5.32
-1.17
-1.46
-0.0366
-0.14
0.47
0.14
42.53
60.94
0.0938
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1411.34
-17.15
49.0
52.0
109.0
242.0
6.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161500 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Calcitonin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone
RECORD: Rec_0246688 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 56.2%, E 0.0%, T 25.0%, C 18.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0324962 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0354662 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Calcitonin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone Calcium-regulatory peptide
Evidence URLhttps://www.uniprot.org/uniprotkb/CALC_MOUSE/entry
RECORD: Rec_0357017 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Calcitonin
10090
Structure & Mods
disulfide-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Amidation
1-7
3:N-linked (GlcNAc...) asparagine
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory Feeding regulator
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Calcitonin (Mus musculus): PMID 8806650 PMID8806650 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8806650/