Peptide Database

Peptide NameDefensin-like protein 1 (Cysteine-rich antifungal protein 1) (AFP1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC389H600N104O105S10

DescriptionStandard

        MAKFASIIALLFAALVLFAAFEAPTMVEAQKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
    

Molecular Weight8734.21 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.60

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0325

GRAVY Index0.34

Hydrophobic Moment 0.44

Boman Index0.18

Instability Index30.55

Aliphatic Index 78.25

Aromaticity 0.1125

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3309.87

LogP -30.33

H-bond Donors 119.0

H-bond Acceptors 120.0

Rotatable Bonds 279.0

Heavy Atoms 608.0

Ring Count 16.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0274767 VERIFIED: YES

Provenance & Taxonomy

OrganismRaphanus sativus [other]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Defense peptide Non-hemolytic

TargetNo Target Organism Found

RECORD: Rec_0298998 VERIFIED: NO

Provenance & Taxonomy

OrganismRaphanus sativus [Plant]

FamilyDefensin

Tax ID3726

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Non-hemolytic Non-ribosomal