‹ ›
MYP_015280
← PREVIOUS NEXT → BACK
Basic Information
K22.2 (Derived from ATG16)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RWKRHISEQLRRRDRLQRQAX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0002683 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
Amidation
The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
17.5-35 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0003911 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Acylation (Arg1 conjugated with myristoyl group)
Amidation
The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
mouse blood cells
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0006236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Acylation (Arg1 conjugated with palmitoyl group)
Amidation
The 'J' in the sequence is the 2-naphthyl alanine (2-Nal) residue
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacteria: Staphylococcus aureus
1.8-3.2 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0012548 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Myristoylation
Amidation
(3-(2-naphthyl)-L-alanine) at 21; (3-(2-naphthyl)-L-alanine)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3.2 - 6.4 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
RECORD: Rec_0015816 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
non-canonical residue code at 21
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
30 - 60 μM
MIC
PMID31145591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31145591/
1 2 3 ... 14 NEXT LAST
Showing 5 records on this page · Page 1 of 14