‹ ›
MYP_015271
← PREVIOUS NEXT → BACK
Basic Information
Teixobactin derivative 4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C63H111N15O15
Standard
Sequence
FISQIIKTKKI
Physicochemical Analysis
1318.65 Da
10.30
2.76
2.55
0.2506
0.37
0.34
0.10
11.16
141.82
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.93
-2.30
18.0
18.0
48.0
93.0
1.0
11.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0341386 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Methylation
N-methylated phenylalanine. Small letter denote D-amino acid. Isoleucine at 5th position is allo-isoleucine. Ester bond formation between 't' and terminal 'I'.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
16 μg/mL
MIC
PMID30050518;28795807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30050518/
RECORD: Rec_0365750 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Methylation
N-methylated phenylalanine. Small letter denote D-amino acid. Isoleucine at 5th position is allo-isoleucine. Ester bond formation between 't' and terminal 'I'.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 29213
4 μg/mL
MIC
PMID30050518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30050518/
RECORD: Rec_0401030 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Methylation
N-methylated phenylalanine. Small letter denote D-amino acid. Isoleucine at 5th position is allo-isoleucine. Ester bond formation between 't' and terminal 'I'.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
64 μg/mL
MIC
PMID30050518;28795807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30050518/
RECORD: Rec_0408599 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Methylation
N-methylated phenylalanine. Small letter denote D-amino acid. Isoleucine at 5th position is allo-isoleucine. Ester bond formation between 't' and terminal 'I'.
Bio-Activity Profile
Hemolytic
RBC
>64 μg/mL
Hemolysis
PMID30050518;28795807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30050518/
FIRST PREV 1 2
Showing 4 records on this page · Page 2 of 2