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MYP_015245
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Basic Information
B. pascuorum defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Standard
40 amino acids
C173H284N56O54S7
Standard
Sequence
ATCDLLSMWNVNHSACAAHCLLLGKSGGRCNDDAVCVCRK
Physicochemical Analysis
4236.90 Da
7.83
0.91
0.53
0.0228
0.20
0.54
0.04
30.41
83.00
0.0250
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1769.30
-22.32
68.0
64.0
139.0
290.0
4.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010886 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0037718 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0095135 VERIFIED: NO
Provenance & Taxonomy
Stable fly [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0119204 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli at 24 uM byitself
PaperMidgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans.
RECORD: Rec_0163351 VERIFIED: YES
Provenance & Taxonomy
Stomoxys calcitrans [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 9326639 PMID9326639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9326639/
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