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MYP_015244
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Basic Information
Unnamed
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
20 amino acids
C96H143N23O32
Standard
Sequence
SEFAYGSFVRTVSLPVGADE
Physicochemical Analysis
2131.30 Da
4.43
-2.53
-2.74
-0.1264
0.19
0.43
0.19
21.41
73.00
0.1500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.38
-9.31
31.0
30.0
65.0
151.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0112033 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory
T cell assay
PaperBalachandran Manavalan et al. AIPpred: Sequence-Based Prediction of Anti-inflammatory Peptides Using Random Forest. Front Pharmacol. 2018. PMID: 29636690. https://pubmed.ncbi.nlm.nih.gov/29636690/ ; https://pmc.ncbi.nlm.nih.gov/articles/PMC5881105/ PMID29636690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29636690/
RECORD: Rec_0134269 VERIFIED: YES
Provenance & Taxonomy
Mycobacterium tuberculosis [Bacterium]
Protein-derived peptide
1773
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
None
Disulfide linkage reported
Conjugated to TLR2-ligand Pam2Cys
Bio-Activity Profile
Immunomodulatory
Female BALB/c mice (6-8 wk, 20±2 g)
20 nmol
LD50
PMID24434326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24434326/
RECORD: Rec_0316231 VERIFIED: YES
Provenance & Taxonomy
Mycobacterium tuberculosis [Bacterium]
Protein-derived peptide
1773
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Immunomodulatory
Female BALB/c mice (6-8 wk, 20±2 g)
20 nmol
LD50
PMID24434326 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24434326/