Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length147 amino acids

Chemical FormulaC616H985N169O210S5

DescriptionStandard

        MTTKSKFGSLARAGAAVALAAGLTAAFQPAAVAATPAVTVTPATGLADGDTVTVKGTGLTPGVVYHVAQCELVTSGSYGCDPTTVVDVTADAQGEVTAQITVHRTFEAVKGADGTPSGTVDCSVSACQVGLGDDFGQGGGGQQITFG
    

Molecular Weight14278.74 Da

Isoelectric Point (pI)4.47

Net Charge (pH 7.0)-6.35

Net Charge (pH 7.4) -6.75

Charge Density (pH 7.0) -0.0432

GRAVY Index0.27

Hydrophobic Moment 0.50

Boman Index0.23

Instability Index8.85

Aliphatic Index 77.01

Aromaticity 0.0476

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5943.64

LogP -82.07

H-bond Donors 208.0

H-bond Acceptors 211.0

Rotatable Bonds 452.0

Heavy Atoms 1000.0

Ring Count 15.0

Amide Bonds 154.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188972 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces taklimakanensis [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal