Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length209 amino acids

Chemical FormulaC1058H1621N239O315S13

DescriptionStandard

        LCIHKIISMFFVIFCVLSTTLTAIMQIDDLAEVDYSLSGLPTVFQTFIDLDLKGVVFPAGNHTDSPYMAASFTIPDHSDSMLYLAFSEYFFQSSSFAYYTAGAFNMTIADETCSFFNINTEIFSSIIPEVAKYSVTPYPVMLKLMSAEIPIISLQQDSFMVEIQGSVEVLAILPDSTTQSLFTLNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight23145.44 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-13.99

Net Charge (pH 7.4) -14.45

Charge Density (pH 7.0) -0.0670

GRAVY Index0.53

Hydrophobic Moment 0.55

Boman Index0.29

Instability Index44.47

Aliphatic Index 102.20

Aromaticity 0.1244

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12170.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138603 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodinocichla rosea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria