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MYP_015157
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV cross
Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV ▸ Anti-HPIV3 cross
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
35 amino acids
C167H286N48O54
Standard
Sequence
KLKEAIRDTNKAVQSVQSSIGNLIVAIKSVQDYVN
Physicochemical Analysis
3830.35 Da
9.40
1.76
1.55
0.0503
-0.15
0.71
-0.03
31.88
116.86
0.0286
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1710.52
-19.56
58.0
56.0
135.0
269.0
1.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098574 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 82.9%, E 0.0%, T 5.7%, C 11.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0244204 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV Anti-Influenza Anti-HPIV3
Human parainfluenza virus 3
PaperLong-lasting antiviral fusion inhibitor peptide conjugates comprising albumin and human immunodeficiency virus (HIV) peptides Evidence URLhttps://patents.google.com/patent/US7582301B1/en PatentUS 7582301 B1
RECORD: Rec_0290875 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Human parainfluenza virus type 3 (Hemagglutinin-Neuraminidase)
Cell-fusion assay
PaperMethods and compositions for inhibition of membrane fusion-associated events | Shawn O'Lin, Dennis Michael, Stephen Robert | Trimeris, Inc., Durham NC (US) | Patent:US6951717 Evidence URLhttps://patents.google.com/patent/US6951717/en PatentUS6951717
RECORD: Rec_0316876 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Respiratory syncytial virus fusion-inhibitory peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-Influenza Anti-RSV Anti-HPIV3 Fusion inhibitor
Human parainfluenza virus 3
PaperHuman respiratory syncytial virus peptides with antifusogenic and antiviral activities Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
RECORD: Rec_0375301 VERIFIED: YES
Provenance & Taxonomy
Human parainfluenza virus 3 [Virus]
Virus-derived peptide
11216;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Human parainfluenza virus type 3 (Fusion); Vero
Immunoprecipitation
PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656
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