Peptide Database

Peptide NameBeta-defensin 1 (Beta-defensin 103)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC339H557N109O81S8

DescriptionStandard

        MRIHYLLFALLFLFLMPAPGEGGLINTVQRYFCRVRGGRCAALTCLPRETQIGHCSVRGRKCCRRRK
    

Molecular Weight7712.25 Da

Isoelectric Point (pI)10.80

Net Charge (pH 7.0)10.62

Net Charge (pH 7.4) 10.20

Charge Density (pH 7.0) 0.1585

GRAVY Index0.05

Hydrophobic Moment 0.81

Boman Index-0.07

Instability Index47.66

Aliphatic Index 88.81

Aromaticity 0.0896

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3073.10

LogP -26.76

H-bond Donors 119.0

H-bond Acceptors 102.0

Rotatable Bonds 255.0

Heavy Atoms 537.0

Ring Count 11.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011252 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Tax ID10181

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal