Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC360H573N101O106S9

DescriptionStandard

        MYNSWGAWVAQSVERPTSAQVMISQSVSSTEKCWNLRGSCREKCIKNEKSYVFCMSGKLCCVKPKFQPKSLQT
    

Molecular Weight8300.60 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.12

Charge Density (pH 7.0) 0.0882

GRAVY Index-0.43

Hydrophobic Moment 0.50

Boman Index-0.08

Instability Index53.43

Aliphatic Index 54.66

Aromaticity 0.0959

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3390.98

LogP -38.37

H-bond Donors 125.0

H-bond Acceptors 122.0

Rotatable Bonds 278.0

Heavy Atoms 576.0

Ring Count 13.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177557 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence