Peptide Database

Peptide NameBac5 (1-17)[P4W]

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC110H163N33O19

DescriptionStandard

        RFRWPIRRPPIRPPFYP
    

Molecular Weight2251.68 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2799

GRAVY Index-1.16

Hydrophobic Moment 0.41

Boman Index-0.34

Instability Index159.88

Aliphatic Index 45.88

Aromaticity 0.2353

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 821.70

LogP -2.24

H-bond Donors 29.0

H-bond Acceptors 24.0

Rotatable Bonds 59.0

Heavy Atoms 162.0

Ring Count 11.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0082754 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative Anticancer Hemolytic

TargetEscherichia coli BW25113

Activity8 μM

MethodMIC

RECORD: Rec_0432101 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxicity assessment Cell viability

TargetMEC-1 leukemia cells

Activity82 %

MethodMTT cell viability assay (32 μM peptide exposure)