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MYP_015097
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Basic Information
HYL-15 (Derived from HYL)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C86H164N22O18
Standard
Sequence
GILKSLLKKLKKIIAK
Physicochemical Analysis
1794.36 Da
10.70
5.75
5.54
0.3596
0.37
0.77
0.02
-10.43
176.88
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
676.17
-1.59
24.0
24.0
70.0
126.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187832 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
24 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0232158 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa 5482
5 μM
MIC
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0258953 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
400 μM
LC50
PaperAntimicrobial Peptide from the Wild Bee Hylaeus signatus Venom and Its Analogues: Structure-Activity Study and Synergistic Effect with Antibiotics PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0270196 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
2.2 μM
MIC
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
RECORD: Rec_0306397 VERIFIED: YES
Provenance & Taxonomy
Hylaeus signatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCs
400 μM
LC50
PMID26998557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26998557/
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