Peptide Database

Peptide NameAtrial natriuretic factor

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC124H213N47O40S5

DescriptionStandard

        MMRDSGCFGRRIDRIGSLSGMGCNGSRKN
    

Molecular Weight3162.63 Da

Isoelectric Point (pI)10.66

Net Charge (pH 7.0)3.48

Net Charge (pH 7.4) 3.23

Charge Density (pH 7.0) 0.1201

GRAVY Index-0.68

Hydrophobic Moment 0.81

Boman Index-0.27

Instability Index31.31

Aliphatic Index 40.34

Aromaticity 0.0345

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1455.34

LogP -21.62

H-bond Donors 56.0

H-bond Acceptors 49.0

Rotatable Bonds 112.0

Heavy Atoms 216.0

Ring Count 1.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056843 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyAtrial natriuretic factor

Tax ID9031

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-23

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0203174 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyAtrial natriuretic factor

Tax ID9031

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-23

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Growth regulation Development regulation Receptor modulation

TargetNPR1 receptor

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0220941 VERIFIED: NO

Provenance & Taxonomy

OrganismGallus gallus [Animal]

Tax ID9031

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-23

Bio-Activity Profile

Function

Neuropeptide