MYP_015056
Pesticidal crystal protein cry11Bb (35-60)
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Insecticidal/Pest control
▸
Insecticidal activity
Standard
26 amino acids
C134H219N33O31
Standard
VAPIAKYLATALAKWALKQGFAKLKS
2788.37 Da
10.30
4.73
4.51
0.1818
0.41
0.48
0.20
10.54
113.08
0.1154
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1031.70
-5.12
36.0
36.0
92.0
198.0
5.0
26.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0118242
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0151369
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Streptococcus pneumoniae ATCC 49619[90-100% Inhibition = 7.1 microM
RECORD: Rec_0218374
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0250322
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
frog Temporin-HN1. Artificially synthesized based on the bacterial Cry11Bb protein, which is toxic to mosquito larvae. The sequence has been patented. At 7.1 uM, this synthetic peptide inhibited the growth of E. coli ATCC 25922, S. aureus ATCC 25923, S. pneumoniae ATCC 49619, H. influenzae ATCC 49247, E. faecalis ATCC 29212, P. aeruginosa ATCC27603, P. aeruginosa (Multi-Resistant), and K. pneumoniae ATCC70603 (Segura C et al., 2007). In addition, the protease-resistant BTM-P1d (i.e., synthesized using D-amino acids), not the BTM-P1 synthesized in L-amino acids, displayed A. aegypti larval toxicity (Lemeshko VV, Orduz S., 2013). It adopts a helical conformation in 30% TFE. MOA: it appears to permeate membranes. Deposited and provided by Sergio Orduz on May 6, 2014. APD release May 8, 2014
Bio-Activity Profile
Antimicrobial
Insecticidal
RECORD: Rec_0277552
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Pseudomonas aeruginosa[80-90% Inhibition = 7.1 microM
Showing 5 records on this page · Page 2 of 3