Peptide Database

Peptide NameRattusin

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC145H259N57O43S5

DescriptionStandard

        LRVRRTLQCSCRRVCRNTCSCIRLSRSTYAS
    

Molecular Weight3649.29 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)7.71

Net Charge (pH 7.4) 7.43

Charge Density (pH 7.0) 0.2487

GRAVY Index-0.38

Hydrophobic Moment 0.79

Boman Index-0.45

Instability Index111.23

Aliphatic Index 72.26

Aromaticity 0.0323

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1699.77

LogP -24.59

H-bond Donors 72.0

H-bond Acceptors 56.0

Rotatable Bonds 123.0

Heavy Atoms 250.0

Ring Count 1.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280713 VERIFIED: YES

Provenance & Taxonomy

OrganismPaneth cells [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetListeria monocytogenes

Activity2-8 μM

MethodMIC

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