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MYP_014998
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Basic Information
Rattusin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
31 amino acids
C145H259N57O43S5
Standard
Sequence
LRVRRTLQCSCRRVCRNTCSCIRLSRSTYAS
Physicochemical Analysis
3649.29 Da
11.20
7.71
7.43
0.2487
-0.38
0.79
-0.45
111.23
72.26
0.0323
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1699.77
-24.59
72.0
56.0
123.0
250.0
1.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0041000 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0067182 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Cytotoxic
RECORD: Rec_0094378 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0164671 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923; Staphylococcus aureus ATCC BAA-39; Staphylococcus aureus ATCC 43300; Listeria monocytogenes ATCC 19115; Escherichia coli O157:H7 ATCC 700728; Salmonella enterica serovar Typhimurium ATCC 14028; Salmonella enterica serovar Typhimurium DT104 ATCC 700408; Klebsiella pneumoniae ATCC 13883
Modified broth microdilution antibacterial assay
PMID23380721 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23380721/
RECORD: Rec_0254117 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23380721 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23415652/
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