Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC186H311N61O50S7

DescriptionStandard

        ISNPLSCSRNKGICLPIRCPGSMRQIGTCFGPRVKCCRSW
    

Molecular Weight4426.29 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.1675

GRAVY Index-0.12

Hydrophobic Moment 0.47

Boman Index-0.09

Instability Index50.39

Aliphatic Index 65.75

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1791.04

LogP -21.98

H-bond Donors 70.0

H-bond Acceptors 64.0

Rotatable Bonds 142.0

Heavy Atoms 304.0

Ring Count 7.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010185 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)