Peptide Database

Peptide NameBTD-4 (theta-defensin; primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC82H143N27O20S6

DescriptionStandard

        RCVCTRGFCRCICLLGIC
    

Molecular Weight2019.57 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.1500

GRAVY Index1.31

Hydrophobic Moment 0.67

Boman Index0.12

Instability Index24.63

Aliphatic Index 102.78

Aromaticity 0.0556

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 763.95

LogP -7.26

H-bond Donors 35.0

H-bond Acceptors 29.0

Rotatable Bonds 65.0

Heavy Atoms 135.0

Ring Count 1.0

Amide Bonds 17.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0421631 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

FIRST PREV 1 2 3

Showing 1 records on this page Ã‚Â· Page 3 of 3