Peptide Database

Peptide Namedichotomin E

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Enzyme modulation ▸ Enzyme inhibition ▸ Cyclooxygenase-inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC26H33N5O7

DescriptionStandard

        GYAFA
    

Molecular Weight527.57 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0482

GRAVY Index0.94

Hydrophobic Moment 0.22

Boman Index0.63

Instability Index38.38

Aliphatic Index 40.00

Aromaticity 0.4000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 199.95

LogP -0.80

H-bond Donors 7.0

H-bond Acceptors 7.0

Rotatable Bonds 13.0

Heavy Atoms 38.0

Ring Count 2.0

Amide Bonds 4.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0172322 VERIFIED: YES

Provenance & Taxonomy

OrganismStellaria dichotoma [Plant]

FamilyOrbitide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic Cyclooxygenase-inhibitor

TargetP388 cells