Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC884H1343N201O270S9

DescriptionStandard

        DYSLNSLPAVSRPYIDLDLKGIVYPGGNYTAPPFVATPFTVPDQSDSMLYLAISEYFFQTSSFAYYTAGAFNITIAEETCSYFNISSEIFGSIIPEVAQYSVMPYPVMLKLMATETPIISLQQDSFTLEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIAVNIFDQKLMGSLCLNR
    

Molecular Weight19394.89 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-11.24

Net Charge (pH 7.4) -11.51

Charge Density (pH 7.0) -0.0639

GRAVY Index0.28

Hydrophobic Moment 0.49

Boman Index0.24

Instability Index54.49

Aliphatic Index 90.91

Aromaticity 0.1307

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7448.79

LogP -77.00

H-bond Donors 253.0

H-bond Acceptors 268.0

Rotatable Bonds 612.0

Heavy Atoms 1364.0

Ring Count 35.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095685 VERIFIED: NO

Provenance & Taxonomy

OrganismDromaius novaehollandiae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria