Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC787H1243N231O232S4

DescriptionStandard

        MVGINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV
    

Molecular Weight17780.96 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)4.77

Net Charge (pH 7.4) 4.34

Charge Density (pH 7.0) 0.0302

GRAVY Index-0.60

Hydrophobic Moment 0.68

Boman Index-0.10

Instability Index23.75

Aliphatic Index 78.48

Aromaticity 0.0886

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7551.96

LogP -76.30

H-bond Donors 264.0

H-bond Acceptors 244.0

Rotatable Bonds 602.0

Heavy Atoms 1254.0

Ring Count 26.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071085 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage HK542 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic