Peptide Database

Peptide NameSyn-safencin-2

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC134H231N41O32

DescriptionStandard

        AGKKTIRQYLKNEIKKKGRKAVIAW
    

Molecular Weight2928.52 Da

Isoelectric Point (pI)10.79

Net Charge (pH 7.0)7.79

Net Charge (pH 7.4) 7.59

Charge Density (pH 7.0) 0.3116

GRAVY Index-0.94

Hydrophobic Moment 0.67

Boman Index-0.31

Instability Index8.41

Aliphatic Index 86.00

Aromaticity 0.0800

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1247.39

LogP -9.32

H-bond Donors 45.0

H-bond Acceptors 40.0

Rotatable Bonds 107.0

Heavy Atoms 207.0

Ring Count 3.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015806 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity2.42 μM

MethodIC50

RECORD: Rec_0290061 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity>20 μM

MethodCC50