Peptide Database

Peptide NameCNP-53 (C-type natriuretic peptide)

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC270H453N87O77S3

DescriptionStandard

        DLRVDTKSRAAWARLLQEHPNARKYKGANKKGLSKGGLSKGCFGLKLDRIGSMSGLGC
    

Molecular Weight6246.22 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)8.82

Net Charge (pH 7.4) 8.52

Charge Density (pH 7.0) 0.1521

GRAVY Index-0.62

Hydrophobic Moment 0.55

Boman Index-0.17

Instability Index18.08

Aliphatic Index 74.14

Aromaticity 0.0517

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2695.44

LogP -31.12

H-bond Donors 99.0

H-bond Acceptors 90.0

Rotatable Bonds 220.0

Heavy Atoms 437.0

Ring Count 6.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143069 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyNatriuretic peptide

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide42-58

Bio-Activity Profile

Function

Natriuretic

MethodCompetitive Radioimmunoassay

Half-LifeRat plasma (Intravenous), in vivo; 943.2 s