‹ ›
MYP_014889
← PREVIOUS NEXT → BACK
Basic Information
Fluoromethyl ketone proteinase inhibitor
Antimicrobial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Alanine Carboxypeptidase Inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Standard
2 amino acids
C12H16N2O3
Standard
Sequence
FA
Physicochemical Analysis
236.27 Da
5.53
-0.24
-0.44
-0.1200
2.30
0.62
0.91
5.00
50.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
0.15
3.0
3.0
5.0
17.0
1.0
1.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0339828 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
9925.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-III Inhibitory
Dipeptidyl peptidase III
PaperDhanda S.; Singh H.; Singh J.. Hydrolysis of various bioactive peptides by goat brain dipeptidylpeptidase-III. Cell Biochem. Funct. 23, 3, 339-345, 2008.
RECORD: Rec_0344615 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Mu=morpholine urea
VS=vinyl-sulfone,Me=methyl
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Cysteine protease inhibitor
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0375449 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Protease/Proteasome inhibitor
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Benzyloxycarbonyl
Fluoromethyl ketone
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium falciparum Itg2
0.064 μM
LD50; Microscopy (Giemsa staining)
PMID1939639 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1939639/
RECORD: Rec_0380972 VERIFIED: YES
Provenance & Taxonomy
Amaranthus hypochondriacus [Plant]; Theobroma cacao [Plant]
28502, 3641
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Taste
PaperBioactive peptides in amaranth (Amaranthus hypochondriacus) seed PMID18211015 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18211015/
RECORD: Rec_0404536 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Carbobenzoxy
CH2F
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Cysteine protease inhibitor
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4