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MYP_014864
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Basic Information
Fabatin-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
47 amino acids
C211H352N74O62S9
Standard
Sequence
LLGRCKVKSNRFNGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC
Physicochemical Analysis
5206.10 Da
9.12
5.86
5.43
0.1246
-0.42
0.43
-0.21
43.30
53.83
0.0426
1490.00
1990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2219.41
-28.86
89.0
79.0
175.0
356.0
5.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014461 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/
RECORD: Rec_0019422 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
3906
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterococcus hirae. Gram-negative bacteria: Escherichia coli
PaperPubMed PMID 9725750 | PubMed PMID 4272081 | PubMed PMID 20000000 PMID9725750;4272081;20000000;20000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9725750/
RECORD: Rec_0085827 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
3906
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
PaperPubMed PMID 9725750 | PubMed PMID 4272081 | PubMed PMID 20000000 PMID9725750;4272081;20000000;20000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9725750/
RECORD: Rec_0100328 VERIFIED: YES
Provenance & Taxonomy
Vicia faba [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
PaperPubMed PMID: 9103978 PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/
RECORD: Rec_0150860 VERIFIED: NO
Provenance & Taxonomy
Vicia faba [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Plant Defense Anti-Candida Anti-Yeast Non-hemolytic Non-ribosomal
Saccharomyces cerevisiae
Qualitative functional evidence
PMID9103978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9103978/; https://www.uniprot.org/uniprotkb/P81457/entry; https://bblserver.org.in/ampdb/
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