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MYP_014857
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Basic Information
WI-6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C94H146N22O20
Standard
Sequence
WIQPKTKVIPYVRYL
Physicochemical Analysis
1904.30 Da
10.00
2.76
2.55
0.1837
-0.13
0.37
0.07
9.57
116.67
0.2000
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
686.65
-0.56
24.0
23.0
57.0
136.0
6.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001551 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. enteric CMCC 47020MIC
>128 μM
PMID32569466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32569466/
RECORD: Rec_0008518 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
residues removed
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID23793637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23793637/
RECORD: Rec_0025541 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
256 μM
Hemolysis
PMID32569466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32569466/
RECORD: Rec_0069971 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
residues removed
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. sakazakii
PMID23793637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23793637/
RECORD: Rec_0076045 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S2-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes; Cronobacter sakazakii
MIC
PaperStructure-activity relationship of synthetic variants of the milk-derived antimicrobial peptide αs2-casein f(183-207) | Alvarez-Ordonez, A. et al. | DOI: 10.1128/AEM.01394-13 Evidence URLhttps://www.uniprot.org/uniprotkb/P02663/entry
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