Peptide Database

Peptide NameConotoxin Cal6.4a

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC103H157N33O29S6

DescriptionStandard

        GCWLCLGPNACCRGSVCHDYCPR
    

Molecular Weight2513.94 Da

Isoelectric Point (pI)7.79

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.44

Charge Density (pH 7.0) 0.0343

GRAVY Index0.09

Hydrophobic Moment 0.36

Boman Index0.04

Instability Index68.28

Aliphatic Index 50.87

Aromaticity 0.0870

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 975.06

LogP -11.18

H-bond Donors 40.0

H-bond Acceptors 37.0

Rotatable Bonds 73.0

Heavy Atoms 171.0

Ring Count 6.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0012911 VERIFIED: NO

Provenance & Taxonomy

OrganismConus californicus [Animal]

FamilyConotoxin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0086485 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 34.8%, C 65.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic