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MYP_014836
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C38H59N7O8
Standard
Sequence
GPFPILV
Physicochemical Analysis
741.92 Da
5.53
-0.24
-0.44
-0.0343
1.67
0.13
0.78
91.11
152.86
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
220.34
0.94
6.0
8.0
18.0
53.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0352536 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
9925
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
424±42.4 μM
IC50
PaperAngiotensin-converting enzyme inhibitory activity of peptides derived from caprine kefir PMID16162521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16162521/
RECORD: Rec_0353232 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
Dipeptidyl peptidase IV
163.7
IC50
PaperZhang Y., Chen R., Zuo F., Ma H., Zhang Y., Chen S.. Comparison of dipeptidyl peptidase IV-inhibitory activity of peptides from bovine and caprine milk casein by in silico and in vitro analyses. Int. Dairy J., 53, 37-44, 2016.
RECORD: Rec_0400452 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
beta-Casein-derived
9925
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
424 μM
IC50
PaperAngiotensin-Converting Enzyme Inhibitory Activity of Peptides Derived from Caprine Kefir | Quiros, A. et al. | DOI: 10.3168/jds.S0022-0302(05)73032-0 Evidence URLhttps://www.uniprot.org/uniprotkb/P33048/entry
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