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MYP_014836
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C38H59N7O8
Standard
Sequence
GPFPILV
Physicochemical Analysis
741.92 Da
5.53
-0.24
-0.44
-0.0343
1.67
0.13
0.78
91.11
152.86
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
220.34
0.94
6.0
8.0
18.0
53.0
3.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042570 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV Inhibitory
DPP-IV
424.0 μM
IC50
RECORD: Rec_0087011 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0150920 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
beta-Casein-derived
9925
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
163 μM
IC50
PaperComparison of dipeptidyl peptidase IV-inhibitory activity of peptides from bovine and caprine milk casein by in silico and in vitro analyses | Zhang, Y. et al. | DOI: 10.1016/j.idairyj.2015.10.001 Evidence URLhttps://www.uniprot.org/uniprotkb/P33048/entry
RECORD: Rec_0216951 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
ACE-inhibitory peptide
9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
424 μM
IC50
PaperAngiotensin-converting enzyme inhibitory activity of peptides derived from caprine kefir PMID16162521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16162521/
RECORD: Rec_0307336 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Casein-derived peptide
9925
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
424.0 ± 42.4 μM
IC50
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