‹ ›
MYP_014812
← PREVIOUS NEXT → BACK
Basic Information
Corticostatin-related peptide RK-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
32 amino acids
C159H245N41O47S7
Standard
Sequence
MPCSCKKYCDPWEVIDGSCGLFNSKYICCREK
Physicochemical Analysis
3707.35 Da
7.54
0.44
0.13
0.0138
-0.34
0.44
-0.07
46.56
45.62
0.1250
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1423.05
-13.00
55.0
55.0
120.0
254.0
7.0
32.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0205941 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperBateman A., MacLeod R.J., Lembessis P., Hu J., Esch F., Solomon S.;. "The isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney."; J. Biol. Chem. 271:10654-1065. Evidence URLhttps://www.uniprot.org/uniprotkb/RK1_RABIT/entry
RECORD: Rec_0270503 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
3-29; 5-19; 9-28
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 8631871 | PubMed PMID: 11123900 PMID8631871;11123900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8631871/
RECORD: Rec_0282648 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0317881 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0412512 VERIFIED: YES
Provenance & Taxonomy
European rabbit [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli. It can also activate epithelial ion channels in vitro. Structure: 3 disulfide bridges:3,29; 5,19; 9,28. 3D structure was solved by Mcmanus AM et al. (2000) Biochemistry 39: 15757. You can rotate, zoom
PaperThe isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney.
FIRST PREV 1 2
Showing 5 records on this page · Page 2 of 2