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MYP_014806
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Basic Information
Big defensin (RPD-1)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
11 amino acids
C52H74N12O16
Standard
Sequence
AVPDVAFNAYG
Physicochemical Analysis
1123.21 Da
4.05
-1.20
-1.39
-0.1095
0.57
0.23
0.40
12.03
80.00
0.1818
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
446.15
-3.70
14.0
15.0
30.0
80.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108612 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Staphylococcus aureus
9.6 μg/mL
MIC
PMID14673509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14673509/
RECORD: Rec_0149469 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Micrococcus tetragenus
38.4 μg/mL
MIC
PMID14673509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14673509/
RECORD: Rec_0249005 VERIFIED: YES
Provenance & Taxonomy
Ruditapes philippinarum [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Vibrio parahaemolyticus
PMID14673509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14673509/
RECORD: Rec_0260870 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
Vibrio parahaemolyticus
19.2 μg/mL
MIC
PMID14673509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14673509/
RECORD: Rec_0262303 VERIFIED: YES
Provenance & Taxonomy
Venerupis philippinarum [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Vibrio parahaemoliticus
19.2 μg/mL
MIC
PMID14673509 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14673509/
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