Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length237 amino acids

Chemical FormulaC1201H1838N272O365S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFQPFIDLDLKGIVFPAGNYTDSPYEAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEEVKSGNSFVFSLIFFLQTCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPVISLQQDSFTLEIQGSMEVLAILPDSTTQSLLTLSIAANTSISLNIFNKKLMGSLCLNRIQFSLAHSNVGSFEVLPLENILSYILQTEVIPSANGK
    

Molecular Weight26183.56 Da

Isoelectric Point (pI)4.09

Net Charge (pH 7.0)-15.14

Net Charge (pH 7.4) -15.48

Charge Density (pH 7.0) -0.0639

GRAVY Index0.33

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index45.20

Aliphatic Index 101.22

Aromaticity 0.1266

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0115075 VERIFIED: NO

Provenance & Taxonomy

OrganismPomatorhinus ruficollis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria