Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length109 amino acids

Chemical FormulaC545H881N161O143S11

DescriptionStandard

        MKLLLLVFASFGFLVIPASGGGARCTHKFPGRCKMSCDSLERSIFMCDRYKLCCVKDPLRTIAPPPVHKAQNRCRKTTKRQNEEHQMGIPPKPLSFPSIQHNYRTPIKG
    

Molecular Weight12329.53 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)12.78

Net Charge (pH 7.4) 12.23

Charge Density (pH 7.0) 0.1172

GRAVY Index-0.38

Hydrophobic Moment 0.62

Boman Index-0.09

Instability Index55.97

Aliphatic Index 68.90

Aromaticity 0.0734

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4850.10

LogP -46.89

H-bond Donors 174.0

H-bond Acceptors 171.0

Rotatable Bonds 404.0

Heavy Atoms 860.0

Ring Count 23.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007875 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Tax ID9713

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0191295 VERIFIED: NO