Peptide Database

Peptide NameLL-37 KR-12 [R2A]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC68H119N21O16

DescriptionStandard

        KAIVQRIKDFLR
    

Molecular Weight1486.80 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2299

GRAVY Index-0.18

Hydrophobic Moment 0.75

Boman Index-0.26

Instability Index4.78

Aliphatic Index 130.00

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 639.65

LogP -3.69

H-bond Donors 23.0

H-bond Acceptors 19.0

Rotatable Bonds 53.0

Heavy Atoms 105.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408496 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus ATCC 29213

Activity40 μM

MethodMIC

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