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MYP_014695
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Basic Information
Raniseptin-1 (Rsp-1; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C144H237N39O39
Standard
Sequence
AWLDKLKSLGKVVGKVALGVAQNYLNPQQ
Physicochemical Analysis
3138.66 Da
9.83
2.79
2.60
0.0963
-0.04
0.69
0.10
2.78
117.59
0.0690
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1282.41
-10.51
42.0
42.0
106.0
222.0
4.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013007 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas raniceps [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID18976634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18976634/
RECORD: Rec_0033658 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
5 μM
MIC
PaperPost-secretory events alter the peptide content of the skin secretion of Hypsiboas raniceps.
RECORD: Rec_0037893 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas raniceps [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
10 μM
MIC
PaperPost-secretory events alter the peptide content of the skin secretion of Hypsiboas raniceps.
RECORD: Rec_0052290 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 6.9%, T 41.4%, C 51.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0058333 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas raniceps [Animal]
Raniseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
20.0 μM
MIC
PaperB.S. Magalhaes et al. / BBRC 377 (2008) 1057-1061. Post-secretory events alter the peptide content of the skin secretion of Hypsiboas raniceps Evidence URLhttps://www.uniprot.org/uniprotkb/P86037/entry
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