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MYP_014599
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Basic Information
HR1-5
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
40 amino acids
C184H310N56O57S3
Standard
Sequence
YVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKG
Physicochemical Analysis
4314.97 Da
9.31
2.74
2.50
0.0686
-0.06
0.57
-0.04
57.67
85.50
0.0500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1867.62
-21.89
68.0
63.0
149.0
300.0
2.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077659 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
HR1-derived fusion inhibitor
694009
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
EC50
PaperSuppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein PMID15184046 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15184046/
RECORD: Rec_0279497 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0309034 VERIFIED: YES
Provenance & Taxonomy
Severe acute respiratory syndrome-related coronavirus [Virus]
Heptad repeat peptide
694009;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
SARS coronavirus (Virus entry); 293T
Luciferase assay
PaperSuppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein. | Yuan K, Yi L, Chen J, Qu X, Qing T, Rao X, Jiang P, Hu J, Xiong Z, Nie Y, Shi X, Wang W, Ling C, Yin X, Fan K, Lai L, Ding M, Deng H. | Biochem Biophys Res Commun. 2004 | PMID:15184046 PMID15184046 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15184046/