Peptide Database

Peptide NameNatriuretic peptide TsNP

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC95H156N26O27S3

DescriptionStandard

        KLSGCFGFKLDRIGTMSGLGC
    

Molecular Weight2190.61 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0828

GRAVY Index0.40

Hydrophobic Moment 0.43

Boman Index0.18

Instability Index7.57

Aliphatic Index 74.29

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 857.25

LogP -9.10

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 75.0

Heavy Atoms 151.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014618 VERIFIED: YES

Provenance & Taxonomy

OrganismTityus serrulatus [Animal]

FamilyNatriuretic peptide TsNP

Tax ID6887

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide5-21

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0215987 VERIFIED: NO